TOX3 Antikörper (AA 214-242)

Produktnummer ABIN651009

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-TOX3 Antikörper (Klon RB24743) (ABIN651009) detektiert spezifisch TOX3 in FACS, WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für TOX3 Antikörper (AA 214-242) (ABIN651009)

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOX3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB24743

Produktdetails anti-TOX3 Antikörper

Bindungsspezifität: AA 214-242

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human TOX3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-TOX3 Antikörper (ABIN651009)

Han, Yue, Yang, Jian, Ma, Liu: "TOX3 protein expression is correlated with pathological characteristics in breast cancer." in: Oncology letters, Vol. 11, Issue 3, pp. 1762-1768, (2016) (PubMed).

Details zu TOX3

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Andere Bezeichnung: TOX3

Hintergrund: TOX3 contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer.

Molekulargewicht: 63342

Gen-ID: 27324

NCBI Accession: NP_001073899, NP_001139660

UniProt: O15405

Pathways: Chromatin Binding