SPRN Antikörper (C-Term)

Produktnummer ABIN650950

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPRN in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für SPRN Antikörper (C-Term) (ABIN650950)

Target: SPRN (Shadow of Prion Protein (SPRN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPRN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB25483

Produktdetails anti-SPRN Antikörper

Bindungsspezifität: AA 76-105, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the C-terminal region of human SPRN.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-SPRN Antikörper (ABIN650950)

Nyeste, Stincardini, Bencsura, Cerovic, Biasini, Welker: "The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells." in: Scientific reports, Vol. 6, pp. 36441, (2018) (PubMed).

Nyeste, Bencsura, Vida, Hegyi, Homolya, Fodor, Welker: "Expression of the Prion Protein Family Member Shadoo Causes Drug Hypersensitivity That Is Diminished by the Coexpression of the Wild Type Prion Protein." in: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4473-86, (2016) (PubMed).

Details zu SPRN

Target: SPRN (Shadow of Prion Protein (SPRN))

Andere Bezeichnung: SPRN

Hintergrund: SPRN has PrP(C)-like neuroprotective activity. SPRN may act as a modulator for the biological actions of normal and abnormal PrP.

Molekulargewicht: 14522

Gen-ID: 503542

NCBI Accession: NP_001012526

UniProt: Q5BIV9