Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PHGDH in WB, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PHGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human PHGDH.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Liu, Liu, Yu, Lin, Chu, Deng, Yan, Li, Yao: "Systematic analysis of mRNA expression profiles in NSCLC cell lines to screen metastasis-related genes." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5093-5103, (2017) (PubMed).
Target
PHGDH
(phosphoglycerate Dehydrogenase (PHGDH))
Andere Bezeichnung
PHGDH
Hintergrund
3-Phosphoglycerate dehydrogenase (PHGDH, EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.