Transportin 1 Antikörper (N-Term)

Produktnummer ABIN650673

Dieses Anti-Transportin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Transportin 1 in WB, FACS und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Transportin 1 Antikörper (N-Term) (ABIN650673)

Target: Transportin 1 (TNPO1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transportin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB17873

Produktdetails anti-Transportin 1 Antikörper

Bindungsspezifität: AA 47-74, N-Term

Homologie: B, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-74 amino acids from the N-terminal region of human TNPO1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Transportin 1 Antikörper (ABIN650673)

Conde-Rubio, Mylonas, Widmann: "The proteolytic landscape of cells exposed to non-lethal stresses is shaped by executioner caspases." in: Cell death discovery, Vol. 7, Issue 1, pp. 164, (2021) (PubMed).

Details zu Transportin 1

Target: Transportin 1 (TNPO1)

Andere Bezeichnung: TNPO1

Hintergrund: TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.

Molekulargewicht: 102355

Gen-ID: 3842

NCBI Accession: NP_002261, NP_694858

UniProt: Q92973

Pathways: PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events