Retinoid X Receptor beta Antikörper

Produktnummer ABIN645872

Der Ziege not_set anti-Retinoid X Receptor beta Antikörper wird verwendet zum Nachweis von Retinoid X Receptor beta in Proben von Human, Maus und Ratte.

Kurzübersicht für Retinoid X Receptor beta Antikörper (ABIN645872)

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Konjugat: Dieser Retinoid X Receptor beta Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-Retinoid X Receptor beta Antikörper

Spezifität: The Goat anti-RXR beta antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Produktmerkmale: Goat Anti-RXR beta

Immunogen: Peptide with sequence CRDGMGDSGRDSRSP, from the internal region of the protein sequence according to NP_068811, was used as an immunogen.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Lagerung: -20 °C

Details zu Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Andere Bezeichnung: RXR beta

Hintergrund: Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins that exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).

NCBI Accession: NP_068811

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway