Retinoid X Receptor alpha Antikörper

Produktnummer ABIN645871

Dieser Ziege not_set Antikörper detektiert spezifisch Retinoid X Receptor alpha . Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Retinoid X Receptor alpha Antikörper (ABIN645871)

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Konjugat: Dieser Retinoid X Receptor alpha Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-Retinoid X Receptor alpha Antikörper

Spezifität: The Goat anti-RXR alpha antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Produktmerkmale: Goat Anti-RXR alpha

Immunogen: Peptide with sequence CQVNSSLTSPTGRGSM, from the internal region of the protein sequence according to NP_002948, was used as an immunogen.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Lagerung: -20 °C

Details zu Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Andere Bezeichnung: RXR alpha

Hintergrund: Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins that exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).

NCBI Accession: NP_002948

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C