EBV LMP2A Antikörper
Kurzübersicht für EBV LMP2A Antikörper (ABIN644979)
Target
Reaktivität
Wirt
Konjugat
Applikation
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Spezifität
- DS-MB-03627 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. DS-MB-03627 specifically recognizes LMP2A and does not cross react with LMP2B.
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Produktmerkmale
- Rat Anti-Epstein-Barr Virus LMP2A
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Aufreinigung
- Purified
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Immunogen
- Bacterial TrpE-LMP2A fusion protein
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Isotyp
- IgG2a
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- IgG concentration 1.0 mg/ml
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Buffer
- Phosphate buffered saline
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
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Andere Bezeichnung
- Epstein-Barr Virus LMP2A
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Substanzklasse
- Viral Protein
Target
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