EBV LMP2A Antikörper
EBV LMP2A
Reaktivität: Epstein-Barr Virus (EBV)
IHC (p), WB, IHC
Wirt: Ratte
Monoclonal
15F9
unconjugated
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- Target Alle EBV LMP2A Produkte
- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
- Reaktivität
- Epstein-Barr Virus (EBV)
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Wirt
- Ratte
- Klonalität
- Monoklonal
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Konjugat
- Dieser EBV LMP2A Antikörper ist unkonjugiert
- Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Recognizes LMP2A and does not cross react with LMP2B.
- Aufreinigung
- Affinity purified
- Immunogen
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Bacterial TrpE-LMP2A fusion protein.
Type of Immunogen: Fusion protein - Klon
- 15F9
- Isotyp
- IgG1
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- Applikationshinweise
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Approved: IHC, IHC-P, WB (1:100 - 1:1000)
Usage: Immunohistology: This product requires antigen retrieval using heat treatment methods prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. - Kommentare
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Target Species of Antibody: Epstein-Barr Virus
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
-
Short term: -20°C
Long term: -20°C.
-
- Target
- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
- Andere Bezeichnung
- EBV LMP2A (EBV LMP2A Produkte)
- Synonyme
- - antikoerper, LMP2A antikoerper
- Substanzklasse
- Viral Protein
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