Clusterin Antikörper

Produktnummer ABIN644018

Der Kaninchen Polyklonal anti-Clusterin Antikörper wird verwendet zum Nachweis von Clusterin in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Clusterin Antikörper (ABIN644018)

Target: Clusterin (CLU)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Clusterin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Clusterin Antikörper

Verwendungszweck: Rabbit Anti-Human CLU / ApoJ

Spezifität: DS-PB-00501 recognizes human clusterin (also known as apolipoprotein J). Clusterin is a ubiquitous glycoprotein which exists in at least two distinct isoforms, a proapoptotic nuclear form, of 49kDa, and a prosurvival secretory form with a molecular weight of 75-80kDa. Clusterin is implicated in several diverse physiological processes including sperm maturation, cell differentiation, and apoptosis. Clusterin upregulation has been reported in various human malignancies, including bladder, prostate, and breast tumours. Following specific stress induced injury, secretory clusterin acts as a molecular chaperone, scavenging denatured proteins outside cells. It has been shown to be upregulated in Alzheimer's disease, retinitis pigmentosa, glomerulonephritis, atherosclerosis and myocardial infarction.

Produktmerkmale: Cytoskeleton

Aufreinigung: Purified

Immunogen: Antisera to Clusterin were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistology - Paraffin, Western Blotting

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu Clusterin

Target: Clusterin (CLU)

Andere Bezeichnung: CLUSTERIN

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling