PLVAP Antikörper

Produktnummer ABIN642822

Der Ratte not_set anti-PLVAP Antikörper (ABIN642822) detektiert spezifisch PLVAP in FACS und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für PLVAP Antikörper (ABIN642822)

Target: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Reaktivität: Maus

Wirt: Ratte

Konjugat: Dieser PLVAP Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PLVAP Antikörper

Spezifität: DS-MB-03957 recognizes murine plasmalemma vesicle-associated protein (PLVAP), a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumor angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.

Produktmerkmale: Rat Anti-Mouse PLVAP

Aufreinigung: Purified

Isotyp: IgG2a

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu PLVAP

Target: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Andere Bezeichnung: PLVAP