CD80 Antikörper (FITC)

Produktnummer ABIN642339

Dieser Anti-CD80-Antikörper ist ein Ratte-not_set-Antikörper zum Nachweis von CD80 in FACS. Geeignet für Maus.

Kurzübersicht für CD80 Antikörper (FITC) (ABIN642339)

Target: CD80

Reaktivität: Maus

Wirt: Ratte

Konjugat: Dieser CD80 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CD80 Antikörper (FITC)

Spezifität: DS-MB-03886 recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.

Produktmerkmale: Rat Anti-Mouse CD80, FITC-labeled

Immunogen: BCL1 cells expressing CD80

Isotyp: IgG2a

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 0.1 mg/ml

Buffer: Phosphate buffered saline pH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu CD80

Target: CD80

Andere Bezeichnung: CD80

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints