CD80 Antikörper (FITC)
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- Target Alle CD80 Antikörper anzeigen
- CD80
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Reaktivität
- Maus
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Wirt
- Ratte
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Konjugat
- Dieser CD80 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- DS-MB-03886 recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.
- Produktmerkmale
- Rat Anti-Mouse CD80, FITC-labeled
- Immunogen
- BCL1 cells expressing CD80
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD80 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- IgG concentration 0.1 mg/ml
- Buffer
- Phosphate buffered saline pH7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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- Target
- CD80
- Andere Bezeichnung
- CD80 (CD80 Produkte)
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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