Dieses Anti-Dinitrophenol-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von Dinitrophenol in ELISA und WB. Geeignet für . Dieses Primary Antibody wurde in 1 Publikation zitiert.
ELISA: >1:4,000, WB: >1:2,000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
Supplied as liquid whole serum without preservative
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Fan, Schrott, Snelling, Felty, Graham, McGauly, Arnold, Korneeva: "Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment." in: BMC neuroscience, Vol. 21, Issue 1, pp. 4, (2020) (PubMed).
Target
Dinitrophenol (DNP)
Andere Bezeichnung
DNP
Substanzklasse
Chemical
Hintergrund
Tissues are continually exposed to reactive oxygen species (ROS) that are produced in tissues from metabolism processes or the inflammatory response of leukocytes or macrophages. It is estimated that as much as 1 % of consumed oxygen may be converted to ROS, which can cause damage to various cellular components. Proteins are one of the cellular components most vulnerable to oxidative damage by ROS, which results in an increase in protein carbonyl content. This oxidative modification of proteins can lead to cross-linking, peptide fragmentation, modified residues and the conversion of one amino group to another. If sufficient protein damage accumulates, cell death will occur.