TIMP1 Antikörper

Produktnummer ABIN636692

Der Kaninchen Polyklonal anti-TIMP1 Antikörper wird verwendet zum Nachweis von TIMP1 in Proben von Human. Er wurde validiert für WB, ELISA und InhibAb.

Kurzübersicht für TIMP1 Antikörper (ABIN636692)

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Produktdetails anti-TIMP1 Antikörper

Aufreinigung: Purified

Immunogen: TIMP1 antibody was raised in rabbit using highly pure recombinant human TIMP-1 as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 0.5-2 µg/mL, Inhibition: 5 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu TIMP1

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Andere Bezeichnung: TIMP1

Hintergrund: TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors.

Molekulargewicht: 20.6 kDa (predicted detection band MW)