TNFSF14 Antikörper
Kurzübersicht für TNFSF14 Antikörper (ABIN636620)
Target
Alle TNFSF14 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Purified
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Immunogen
- LIGHT antibody was raised in rabbit using highly pure recombinant human LIGHT as the immunogen.
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Applikationshinweise
- Optimal conditions should be determined byt he investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Konzentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
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Hintergrund
- LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.
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Molekulargewicht
- 20.1 kDa (predicted detection band MW)
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Pathways
- Cancer Immune Checkpoints
Target
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