TWEAK Antikörper
Kurzübersicht für TWEAK Antikörper (ABIN636584)
Target
Alle TWEAK (TNFSF12) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Purified
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Immunogen
- TWEAK antibody was raised in goat using highly pure recombinant human TWEAK as the immunogen.
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Applikationshinweise
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ELISA: 0.5-2 µg/mL, Inhibition: 0.1-0.2 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Konzentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
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Andere Bezeichnung
- TWEAK
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Hintergrund
- TWEAK belongs to the TNF family of ligands and signals through TWEAKR also known as TNFRSF12A. TWEAK is expressed in a variety of tissues, including the adult heart, pancreas, skeletal muscle, small intestine, spleen and peripheral blood lymphocytes. TWEAK has the ability to induce NF kb activation and chemokine secretion, and to exert an apoptotic activity in certain cells, such as HT-29 human adenocarcinoma cells when cultured in the presence of IFN-gamma. TWEAK also promotes proliferation and migration of endothelial cells.
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Molekulargewicht
- 17 kDa (predicted detection band MW)
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Pathways
- Apoptose
Target
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