CCL3 Antikörper

Produktnummer ABIN636568

Produktdetails anti-CCL3 Antikörper

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Aufreinigung: Purified

Immunogen: MIP1 alpha antibody was raised in rabbit using highly pure recombinant murine MIP-1 a as the immunogen.

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu CCL3

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Andere Bezeichnung: MIP1 alpha (CCL3 Produkte)

Synonyme: MIP-1alpha antikoerper, G0S19-1 antikoerper, LD78ALPHA antikoerper, MIP-1-alpha antikoerper, MIP1A antikoerper, SCYA3 antikoerper, MIP-1a antikoerper, Scya3 antikoerper, AI323804 antikoerper, LD78alpha antikoerper, MIP1-(a) antikoerper, MIP1-alpha antikoerper, Mip1a antikoerper, CCL3L1 antikoerper, CCL3L3 antikoerper, chemokine (C-C motif) ligand 3 antikoerper, C-C motif chemokine ligand 3 antikoerper, CCL3 antikoerper, Ccl3 antikoerper

Hintergrund: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.

Molekulargewicht: 7.8 kDa (predicted detection band MW)

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagie