PUMA Antikörper

Produktnummer ABIN636281

Der Kaninchen Polyklonal anti-PUMA Antikörper wird verwendet zum Nachweis von PUMA in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für PUMA Antikörper (ABIN636281)

Target: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PUMA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PUMA Antikörper

Aufreinigung: Affinity chromatography purified

Immunogen: PUMA antibody was raised in rabbit using 17 residue sequence 29-55 [EQHLESPVPSAPGALAG] found in the exon-3-encoded region in the human PUMA-Alpha and PUMA-Beta forms of the protein as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu PUMA

Target: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Andere Bezeichnung: PUMA

Hintergrund: PUMA (p53 upregulated modulator of apoptosis) is a target for activation by the p53 tumor-suppressor gene. Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.

Pathways: p53 Signalweg, Positive Regulation of Endopeptidase Activity