NDUFA13 Antikörper (AA 159-172)

Produktnummer ABIN636278

Produktdetails anti-NDUFA13 Antikörper

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Bindungsspezifität: AA 159-172

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDUFA13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität (Details): This antibodys immunogens shares 85 % sequence identity with its Mouse and rat homologs.

Aufreinigung: Affinity chromatography purified

Immunogen: GRIM19 antibody was raised in rabbit using AA 159-172 QAETDRRTLQMLRE of the human GRIM-19 protein as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Andere Bezeichnung: GRIM19 (NDUFA13 Produkte)

Synonyme: GRIM-19 antikoerper, Ndufa13 antikoerper, B16.6 antikoerper, CDA016 antikoerper, GRIM19 antikoerper, 2700054G14Rik antikoerper, AU022060 antikoerper, CGI-39 antikoerper, Grim19 antikoerper, RGD1565358 antikoerper, YJEFN3 antikoerper, NADH:ubiquinone oxidoreductase subunit A13 antikoerper, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antikoerper, cell death-regulatory protein GRIM19 antikoerper, GRIM-19 protein antikoerper, NADH:ubiquinone oxidoreductase subunit A13 L homeolog antikoerper, ndufa13 antikoerper, LOC655421 antikoerper, Ndufa13 antikoerper, CpipJ_CPIJ000908 antikoerper, Bm1_18845 antikoerper, ndufa13.L antikoerper, NDUFA13 antikoerper

Hintergrund: Antisense expression of Genes associated with Retinoid-IFN-induced Mortality (GRIM), GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination.

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling