NDUFA13 Antikörper (N-Term)

Produktnummer ABIN6263558

Produktdetails anti-NDUFA13 Antikörper

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDUFA13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: NDUFA13 Antibody detects endogenous levels of total NDUFA13.

Homologie: Pig,Zebrafish,Bovine,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NDUFA13, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Andere Bezeichnung: NDUFA13 (NDUFA13 Produkte)

Synonyme: GRIM-19 antikoerper, Ndufa13 antikoerper, B16.6 antikoerper, CDA016 antikoerper, GRIM19 antikoerper, 2700054G14Rik antikoerper, AU022060 antikoerper, CGI-39 antikoerper, Grim19 antikoerper, RGD1565358 antikoerper, YJEFN3 antikoerper, NADH:ubiquinone oxidoreductase subunit A13 antikoerper, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antikoerper, cell death-regulatory protein GRIM19 antikoerper, GRIM-19 protein antikoerper, NADH:ubiquinone oxidoreductase subunit A13 L homeolog antikoerper, ndufa13 antikoerper, LOC655421 antikoerper, Ndufa13 antikoerper, CpipJ_CPIJ000908 antikoerper, Bm1_18845 antikoerper, ndufa13.L antikoerper, NDUFA13 antikoerper

Hintergrund:

Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed:27626371). Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:27626371). Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes (PubMed:15753091).

Gene: NDUFA13

Molekulargewicht: 17kDa

Gen-ID: 51079

UniProt: Q9P0J0

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling