EDAR Antikörper (Middle Region)

Produktnummer ABIN636121

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EDAR in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für EDAR Antikörper (Middle Region) (ABIN636121)

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EDAR Antikörper

Bindungsspezifität: Middle Region

Spezifität: Ectodysplasin A Receptor antibody was raised against the middle region of EDAR

Aufreinigung: Affinity purified

Immunogen: Ectodysplasin A Receptor antibody was raised using the middle region of EDAR corresponding to a region with amino acids PAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGV

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

Ectodysplasin A Receptor Blocking Peptide, (ABIN5613300), is also available for use as a blocking control in assays to test for specificity of this Ectodysplasin A Receptor antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EDAR antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu EDAR

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Andere Bezeichnung: Ectodysplasin A Receptor

Hintergrund: EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Molekulargewicht: 48 kDa (MW of target protein)

Pathways: Tube Formation, Ubiquitin Proteasome Pathway