Prohibitin Antikörper (C-Term)

Produktnummer ABIN634116

Dieses Anti-Prohibitin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Prohibitin in WB und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Prohibitin Antikörper (C-Term) (ABIN634116)

Target: Prohibitin (PHB)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prohibitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Prohibitin Antikörper

Bindungsspezifität: C-Term

Spezifität: Prohibitin antibody was raised against the C terminal of PHB

Aufreinigung: Affinity purified

Immunogen: Prohibitin antibody was raised using the C terminal of PHB corresponding to a region with amino acids AEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLS

Anwendungsinformationen

Applikationshinweise: WB: 1-2 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

Prohibitin Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this Prohibitin antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHB antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu Prohibitin

Target: Prohibitin (PHB)

Andere Bezeichnung: Prohibitin

Hintergrund: Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

Molekulargewicht: 30 kDa (MW of target protein)

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling