EIF3E Antikörper (N-Term)
Kurzübersicht für EIF3E Antikörper (N-Term) (ABIN632164)
Target
Alle EIF3E Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- EIF3 E antibody was raised against the N terminal of EIF3
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Aufreinigung
- Affinity purified
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Immunogen
- EIF3 E antibody was raised using the N terminal of EIF3 corresponding to a region with amino acids ELLQGKLDLLSDTNMVDFAMDVYKNLYSDDIPHALREKRTTVVAQLKQLQ
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Applikationshinweise
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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EIF3E Blocking Peptide, (ABIN937943), is also available for use as a blocking control in assays to test for specificity of this EIF3E antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EIF0 antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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Andere Bezeichnung
- EIF3E
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Hintergrund
- EIF3E belongs to the eIF-3 subunit E family.It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3E is required for nonsense-mediated mRNA decay (NMD), It may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. The protein may interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
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Molekulargewicht
- 52 kDa (MW of target protein)
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
Target
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