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CAMLG Antikörper (N-Term)

CAMLG Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN630925
  • Target Alle CAMLG Antikörper anzeigen
    CAMLG (Calcium Modulating Ligand (CAMLG))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 39
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 36
    • 6
    • 1
    Kaninchen
    Klonalität
    • 40
    • 3
    Polyklonal
    Konjugat
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CAMLG Antikörper ist unkonjugiert
    Applikation
    • 33
    • 19
    • 14
    • 6
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB)
    Spezifität
    CAMLG antibody was raised against the N terminal of CAMLG
    Aufreinigung
    Affinity purified
    Immunogen
    CAMLG antibody was raised using the N terminal of CAMLG corresponding to a region with amino acids LLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRV
    Top Product
    Discover our top product CAMLG Primärantikörper
  • Applikationshinweise
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    CAMLG Blocking Peptide, catalog no. 33R-5170, is also available for use as a blocking control in assays to test for specificity of this CAMLG antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CAMLG antibody in PBS
    Konzentration
    Lot specific
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    CAMLG (Calcium Modulating Ligand (CAMLG))
    Andere Bezeichnung
    CAMLG (CAMLG Produkte)
    Synonyme
    MGC53900 antikoerper, CAML antikoerper, AI385748 antikoerper, Camlg antikoerper, Caml antikoerper, calcium modulating ligand L homeolog antikoerper, calcium modulating ligand antikoerper, camlg.L antikoerper, CAMLG antikoerper, camlg antikoerper, Caml antikoerper, Camlg antikoerper
    Hintergrund
    The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
    Molekulargewicht
    33 kDa (MW of target protein)
    Pathways
    EGFR Signaling Pathway
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