Gephyrin Antikörper (Middle Region)

Produktnummer ABIN630878

Produktdetails anti-Gephyrin Antikörper

Target: Gephyrin (GPHN)

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gephyrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Gephyrin antibody was raised against the middle region of GPHN

Aufreinigung: Affinity purified

Immunogen: Gephyrin antibody was raised using the middle region of GPHN corresponding to a region with amino acids GEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEV

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

Gephyrin Blocking Peptide, catalog no. 33R-3243, is also available for use as a blocking control in assays to test for specificity of this Gephyrin antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GPHN antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu Gephyrin

Target: Gephyrin (GPHN)

Andere Bezeichnung: Gephyrin (GPHN Produkte)

Synonyme: 5730552E08Rik antikoerper, AI662856 antikoerper, BC027112 antikoerper, C230040D23 antikoerper, GPH antikoerper, GPHRYN antikoerper, geph antikoerper, Geph antikoerper, GPHN antikoerper, GEPH antikoerper, HKPX1 antikoerper, gpgb1 antikoerper, DKFZp459M0825 antikoerper, gephyrin antikoerper, gephyrin L homeolog antikoerper, gephyrin a antikoerper, Gphn antikoerper, GPHN antikoerper, gphn.L antikoerper, gphna antikoerper, PTRG_08978 antikoerper, VDBG_00775 antikoerper, Tsp_03043 antikoerper, gphn antikoerper

Hintergrund: GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

Molekulargewicht: 80 kDa (MW of target protein)

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development