H2AFY Antikörper (Middle Region)

Produktnummer ABIN630687

Dieses Anti-H2AFY-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von H2AFY in WB. Geeignet für Human und Ratte.

Kurzübersicht für H2AFY Antikörper (Middle Region) (ABIN630687)

Target: H2AFY (H2A Histone Family, Member Y (H2AFY))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-H2AFY Antikörper

Bindungsspezifität: Middle Region

Spezifität: H2 AFY antibody was raised against the middle region of H2 FY

Aufreinigung: Affinity purified

Immunogen: H2 AFY antibody was raised using the middle region of H2 FY corresponding to a region with amino acids PVSKKAGGKKGARKSKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLG

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

H2AFY Blocking Peptide, (ABIN5613917), is also available for use as a blocking control in assays to test for specificity of this H2AFY antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of H0 FY antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu H2AFY

Target: H2AFY (H2A Histone Family, Member Y (H2AFY))

Andere Bezeichnung: H2AFY

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFY is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 39 kDa (MW of target protein)