RUNX1 Antikörper
Kurzübersicht für RUNX1 Antikörper (ABIN6298208)
Target
Alle RUNX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Rabbit Anti-AML1 (Ab-435) Antibody,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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Andere Bezeichnung
- AML1
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Hintergrund
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Target Description: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B- dependent transcriptional activation.
Gene Symbol: RUNX1
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Gen-ID
- 861
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UniProt
- Q01196
Target
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