ARHGEF1 Antikörper

Produktnummer ABIN6298119

Produktdetails anti-ARHGEF1 Antikörper

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF1 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Verwendungszweck: Rabbit Anti-ARHGEF1 Antibody,

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu ARHGEF1

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Andere Bezeichnung: ARHGEF1 (ARHGEF1 Produkte)

Synonyme: arhgef1 antikoerper, cb473 antikoerper, zgc:158261 antikoerper, ARHGEF1 antikoerper, GEF1 antikoerper, LBCL2 antikoerper, LSC antikoerper, P115-RHOGEF antikoerper, SUB1.5 antikoerper, Lbcl2 antikoerper, Lsc antikoerper, Rho guanine nucleotide exchange factor (GEF) 1a antikoerper, Rho guanine nucleotide exchange factor 1 antikoerper, Rho guanine nucleotide exchange factor (GEF) 1 antikoerper, arhgef1a antikoerper, ARHGEF1 antikoerper, arhgef1 antikoerper, Arhgef1 antikoerper

Hintergrund:

Target Description: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2- induced RhoA activation.

Gene Symbol: ARHGEF1

Gen-ID: 9138

UniProt: Q92888

Pathways: Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling