ARHGEF1 Antikörper
Kurzübersicht für ARHGEF1 Antikörper (ABIN6298119)
Target
Alle ARHGEF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- Rabbit Anti-ARHGEF1 Antibody,
-
-
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
-
-
- ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))
-
Andere Bezeichnung
- ARHGEF1
-
Hintergrund
-
Target Description: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2- induced RhoA activation.
Gene Symbol: ARHGEF1
-
Gen-ID
- 9138
-
UniProt
- Q92888
-
Pathways
- Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
Target
-