CD63 Antikörper (PE)

Produktnummer ABIN6297775

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD63 in FACS, IF und T. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CD63 Antikörper (PE) (ABIN6297775)

Target: CD63

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD63 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Produktdetails anti-CD63 Antikörper (PE)

Verwendungszweck: Mouse anti-Human/Mouse CD63 Antibody [PE Conjugated]

Spezifität: Cytoplasmic

Aufreinigung: The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.

Immunogen: The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 5 µL/test/million cells or 5 µL/test/100 µL of whole blood
Immunofluorescence: 1:50-1:100 for 30 minutes at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C. The conjugate is light-sensitive, protect from light.

Details zu CD63

Target: CD63

Andere Bezeichnung: CD63 antigen

Hintergrund:

Target Description: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Gene Symbol: CD63///MLA1///TSPAN30

Gen-ID: 967

UniProt: P08962