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CD63 Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD63 in FACS, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6297772

Kurzübersicht für CD63 Antikörper (ABIN6297772)

Target

Alle CD63 Antikörper anzeigen
CD63

Reaktivität

  • 262
  • 104
  • 23
  • 23
  • 23
  • 14
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 186
  • 93
  • 19
  • 4
  • 2
  • 2
  • 1
Maus

Klonalität

  • 245
  • 57
  • 4
Monoklonal

Konjugat

  • 116
  • 21
  • 14
  • 14
  • 13
  • 13
  • 12
  • 11
  • 10
  • 10
  • 10
  • 10
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD63 Antikörper ist unkonjugiert

Applikation

  • 177
  • 135
  • 122
  • 73
  • 53
  • 41
  • 28
  • 27
  • 26
  • 22
  • 18
  • 17
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Verwendungszweck

    Mouse anti-Human CD63 Antibody Cocktail [Sodium Azide Free]

    Spezifität

    Cytoplasmic

    Aufreinigung

    The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.

    Immunogen

    The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.
  • Applikationshinweise

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    In 1X PBS, BSA free, sodium azide free

    Konservierungsmittel

    Azide free

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target

    CD63

    Andere Bezeichnung

    CD63 antigen

    Hintergrund

    Target Description: This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

    Gene Symbol: CD63///MLA1///TSPAN30

    Gen-ID

    967

    UniProt

    P08962
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