CD63 Antikörper

Produktnummer ABIN6297772

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD63 in FACS, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD63 Antikörper (ABIN6297772)

Target: CD63

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD63 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CD63 Antikörper

Verwendungszweck: Mouse anti-Human CD63 Antibody Cocktail [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.

Immunogen: The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CD63

Target: CD63

Andere Bezeichnung: CD63 antigen

Hintergrund:

Target Description: This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Gene Symbol: CD63///MLA1///TSPAN30

Gen-ID: 967

UniProt: P08962