Transferrin Receptor Antikörper

Produktnummer ABIN6297749

Der Maus Monoklonal Anti-Transferrin Receptor-Antikörper wurde für FACS, WB und IF validiert. Er ist geeignet, Transferrin Receptor in Proben von Human zu detektieren.

Kurzübersicht für Transferrin Receptor Antikörper (ABIN6297749)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Transferrin Receptor Antikörper

Verwendungszweck: Mouse anti-Human Transferrin Receptor Antibody [Sodium Azide Free]

Spezifität: Cell surface

Aufreinigung: The KG1 acute myeloid leukemia cell line was used as the immunogen for this Transferrin receptor antibody.

Immunogen: The KG1 acute myeloid leukemia cell line was used as the immunogen for this Transferrin receptor antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 0.25-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: Transferrin receptor protein 1 ]

Hintergrund:

Target Description: This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV). The antibody is highly specific to transferrin receptor and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Gene Symbol: TFRC

Gen-ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis