ICAM-3/CD50 Antikörper

Produktnummer ABIN6297704

Der Maus Monoklonal Anti-ICAM-3/CD50-Antikörper wurde für FACS, IF, IHC, Func und BP validiert. Er ist geeignet, ICAM-3/CD50 in Proben von Human zu detektieren.

Kurzübersicht für ICAM-3/CD50 Antikörper (ABIN6297704)

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICAM-3/CD50 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Functional Studies (Func), Blocking Peptide (BP)

Produktdetails anti-ICAM-3/CD50 Antikörper

Verwendungszweck: Mouse anti-Human CD50 Antibody [Sodium Azide Free]

Spezifität: Cell surface

Aufreinigung: Stimulated human leukocytes were used as the immunogen for this CD50 antibody.

Immunogen: Stimulated human leukocytes were used as the immunogen for this CD50 antibody.

Anwendungsinformationen

Applikationshinweise: Functional Activity (Blocking): Blocks CD50-CD11a interaction
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu ICAM-3/CD50

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Andere Bezeichnung: Intercellular adhesion molecule 3

Hintergrund:

Target Description: This antibody recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM3 (Leucocyte Workshop VI). It is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This CD50 antibody is excellent for staining of formalin/paraffin tissues.

Gene Symbol: ICAM3

Gen-ID: 3385

UniProt: P32942