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ICAM-3/CD50 Antikörper

ICAM3 Reaktivität: Human FACS, IF, IHC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297692
  • Target Alle ICAM-3/CD50 (ICAM3) Antikörper anzeigen
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    Reaktivität
    • 116
    • 3
    • 2
    • 2
    Human
    Wirt
    • 77
    • 38
    • 1
    Maus
    Klonalität
    • 82
    • 34
    Monoklonal
    Konjugat
    • 60
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ICAM-3/CD50 Antikörper ist unkonjugiert
    Applikation
    • 71
    • 46
    • 42
    • 28
    • 26
    • 25
    • 21
    • 13
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Verwendungszweck
    Mouse anti-Human ICAM-3 Antibody [Sodium Azide Free]
    Spezifität
    Cell surface
    Aufreinigung
    Stimulated human leukocytes were used as the immunogen for the ICAM-3 antibody.
    Immunogen
    Stimulated human leukocytes were used as the immunogen for the ICAM-3 antibody.
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  • Applikationshinweise
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    Andere Bezeichnung
    Intercellular adhesion molecule 3 (ICAM3 Produkte)
    Hintergrund

    Target Description: Recognizes an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV & V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC, cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This mAb is excellent for staining of formalin/paraffin tissues.

    Gene Symbol: ICAM3

    Gen-ID
    3385
    UniProt
    P32942
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