CD27 Antikörper

Produktnummer ABIN6297638

Der Maus-Monoklonal Anti-CD27-Antikörper wurde für FACS und IF validiert. Er ist geeignet zum Nachweis von CD27 in Proben aus Human. }

Kurzübersicht für CD27 Antikörper (ABIN6297638)

Target: CD27 (CD27 Molecule (CD27))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD27 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-CD27 Antikörper

Verwendungszweck: Mouse anti-Human CD27 Antibody [Sodium Azide Free]

Spezifität: Cell surface

Aufreinigung: Sezary cells were used as the immunogen for the CD27 antibody.

Immunogen: Sezary cells were used as the immunogen for the CD27 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: CD27 antigen

Hintergrund:

Target Description: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Gene Symbol: CD27///TNFRSF7

Gen-ID: 939

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints