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NKX2-1 Antikörper

NKX2-1 Reaktivität: Human, Maus, Ratte FACS, IF, IHC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297615
  • Target Alle NKX2-1 Antikörper anzeigen
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    Reaktivität
    • 82
    • 37
    • 37
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 54
    • 29
    Maus
    Klonalität
    • 42
    • 41
    Monoklonal
    Konjugat
    • 42
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NKX2-1 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 37
    • 30
    • 27
    • 20
    • 13
    • 12
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Verwendungszweck
    Mouse anti-Human/Mouse/Rat TTF1 Antibody [Sodium Azide Free]
    Spezifität
    Nuclear
    Aufreinigung
    Recombinant protein was used as the immunogen for the TTF1 antibody.
    Immunogen
    Recombinant protein was used as the immunogen for the TTF1 antibody.
    Top Product
    Discover our top product NKX2-1 Primärantikörper
  • Applikationshinweise
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    Andere Bezeichnung
    Homeobox protein Nkx-2.1 (NKX2-1 Produkte)
    Synonyme
    BCH antikoerper, BHC antikoerper, NK-2 antikoerper, NKX2.1 antikoerper, NKX2A antikoerper, TEBP antikoerper, TITF1 antikoerper, TTF-1 antikoerper, TTF1 antikoerper, titf1-A antikoerper, Xnkx-2.1 antikoerper, NKX2-1 antikoerper, LOC100227803 antikoerper, AV026640 antikoerper, Nkx2.1 antikoerper, T/EBP antikoerper, Titf1 antikoerper, Ttf-1 antikoerper, nk2.1a antikoerper, nkx2.1 antikoerper, nkx2.4a antikoerper, titf1 antikoerper, titf1a antikoerper, NK2 homeobox 1 antikoerper, NK2 homeobox 1 L homeolog antikoerper, NK2 homeobox 4b antikoerper, NKX2-1 antikoerper, nkx2-1.L antikoerper, Nkx2-1 antikoerper, nkx2.4b antikoerper
    Hintergrund

    Target Description: Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1. TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.

    Gene Symbol: NKX2-1///NKX2A///TITF1///TTF1

    Gen-ID
    7080
    UniProt
    P43699
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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