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NKX2-1 Antikörper

Dieses Anti-NKX2-1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NKX2-1 in IHC, FACS und IF. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN6297615

Kurzübersicht für NKX2-1 Antikörper (ABIN6297615)

Target

Alle NKX2-1 Antikörper anzeigen
NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Reaktivität

  • 105
  • 63
  • 63
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 62
  • 44
Maus

Klonalität

  • 67
  • 39
Monoklonal

Konjugat

  • 54
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NKX2-1 Antikörper ist unkonjugiert

Applikation

  • 47
  • 45
  • 36
  • 27
  • 25
  • 23
  • 20
  • 9
  • 7
  • 6
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
  • Verwendungszweck

    Mouse anti-Human/Mouse/Rat TTF1 Antibody [Sodium Azide Free]

    Spezifität

    Nuclear

    Aufreinigung

    Recombinant protein was used as the immunogen for the TTF1 antibody.

    Immunogen

    Recombinant protein was used as the immunogen for the TTF1 antibody.
  • Applikationshinweise

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    In 1X PBS, BSA free, sodium azide free

    Konservierungsmittel

    Azide free

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target

    NKX2-1 (NK2 Homeobox 1 (NKX2-1))

    Andere Bezeichnung

    Homeobox protein Nkx-2.1

    Hintergrund

    Target Description: Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1. TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.

    Gene Symbol: NKX2-1///NKX2A///TITF1///TTF1

    Gen-ID

    7080

    UniProt

    P43699

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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