ErbB2/Her2 Antikörper
Kurzübersicht für ErbB2/Her2 Antikörper (ABIN6297525)
Target
Alle ErbB2/Her2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse anti-Human/Rat ErbB2 Antibody HER2 [Sodium Azide Free]
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Spezifität
- Extracellular/Intracellular cell membrane
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Aufreinigung
- Recombinant human protein was used as the immunogen for this ErbB2 antibody.(1)
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Immunogen
- Recombinant human protein was used as the immunogen for this ErbB2 antibody.(1)
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Applikationshinweise
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FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Andere Bezeichnung
- Receptor tyrosine-protein kinase erbB-2
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Hintergrund
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Target Description: This antibody recognizes a protein of 185 kDa, which is identified as HER2 / ErbB2. Its epitope is localized in the extracellular domain. ErbB2 is a member of the EGFR family. This antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. ErbB2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Gene Symbol: ERBB2///HER2///MLN19///NEU///NGL
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Gen-ID
- 2064
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UniProt
- P04626
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
Target
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