MUC6 Antikörper

Produktnummer ABIN6297409

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MUC6 in IHC, IF, WB und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MUC6 Antikörper (ABIN6297409)

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-MUC6 Antikörper

Verwendungszweck: Mouse anti-Human Mucin-6 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic & secreted

Aufreinigung: Recombinant human protein was used as the immunogen for the Mucin-6 antibody.

Immunogen: Recombinant human protein was used as the immunogen for the Mucin-6 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu MUC6

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Andere Bezeichnung: Mucin-6

Hintergrund:

Target Description: MUC6 or gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Gene Symbol: MUC6

Gen-ID: 4588

UniProt: Q6W4X9