IFNA1 Antikörper

Produktnummer ABIN6296890

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IFNA1 in ELISA und Coat. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IFNA1 Antikörper (ABIN6296890)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA1 Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Produktdetails anti-IFNA1 Antikörper

Verwendungszweck: Mouse anti-Human Interferon alpha Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic, extracellular (secreted)

Aufreinigung: Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.

Immunogen: Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.

Anwendungsinformationen

Applikationshinweise: ELISA: order BSA/azide-free format for coating

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Andere Bezeichnung: Interferon alpha-1/13

Hintergrund:

Target Description: This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Gene Symbol: IFNA1///IFNA13

UniProt: P01562

Pathways: JAK-STAT Signalweg, Hepatitis C