UACA Antikörper

Produktnummer ABIN6296769

Dieses Anti-UACA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von UACA in WB, IF und FACS. Geeignet für Human und Maus.

Kurzübersicht für UACA Antikörper (ABIN6296769)

Target: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UACA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-UACA Antikörper

Verwendungszweck: Mouse anti-Human/Mouse UACA Antibody [Sodium Azide Free]

Spezifität: Nuclear membrane

Aufreinigung: Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.

Immunogen: Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu UACA

Target: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Andere Bezeichnung: Uveal autoantigen with coiled-coil domains and ankyrin repeats

Hintergrund:

Target Description: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Gene Symbol: UACA///KIAA1561

Gen-ID: 55075

UniProt: Q9BZF9

Pathways: Positive Regulation of Endopeptidase Activity