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IDH3A Antikörper

Der Kaninchen Polyklonal Anti-IDH3A-Antikörper wurde für WB und IHC validiert. Er ist geeignet, IDH3A in Proben von Human, Ratte, Maus und Hund zu detektieren.
Produktnummer ABIN629675

Kurzübersicht für IDH3A Antikörper (ABIN629675)

Target

Alle IDH3A Antikörper anzeigen
IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Reaktivität

  • 46
  • 32
  • 18
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus, Hund

Wirt

  • 41
  • 4
  • 1
Kaninchen

Klonalität

  • 43
  • 3
Polyklonal

Konjugat

  • 21
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IDH3A Antikörper ist unkonjugiert

Applikation

  • 34
  • 13
  • 13
  • 13
  • 12
  • 10
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Aufreinigung

    Purified

    Immunogen

    IDH3 A antibody was raised using a synthetic peptide corresponding to a region with amino acids MKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLK
  • Applikationshinweise

    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    Kommentare

    IDH3A Blocking Peptide, catalog no. 33R-6142, is also available for use as a blocking control in assays to test for specificity of this IDH3A antibody

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IDH0 antibody in PBS

    Konzentration

    Lot specific

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target

    IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

    Andere Bezeichnung

    IDH3A

    Hintergrund

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.

    Molekulargewicht

    40 kDa (MW of target protein)
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