CD38 Antikörper (Biotin)

Produktnummer ABIN6296645

Der Maus Monoklonal Anti-CD38-Antikörper wurde für ELISA validiert. Er ist geeignet, CD38 in Proben von Human zu detektieren.

Kurzübersicht für CD38 Antikörper (Biotin) (ABIN6296645)

Target: CD38

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD38 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Klon: 2F7-G8-D11

Produktdetails anti-CD38 Antikörper (Biotin)

Verwendungszweck: Mouse anti CD38 (2F7-G8-D11) [+Biotin] Antibody,

Immunogen: Immunogen was recombinant Human CD38 that derived from E.coli. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA (recommended work dilution= 1:1,000,000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution. Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: -20°C

Details zu CD38

Target: CD38

Andere Bezeichnung: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Hintergrund:

Target Description: CD38  (cluster of differentiation  38), also known as  cyclic ADP ribose hydrolase  is a  glycoprotein found on the surface of many immune cells (white blood cells), including  CD4+,  CD8+,  B lymphocytes  andnatural killer cells. CD38 also functions in  cell adhesion,  signal transduction  and  calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. Diseases associated with CD38 include B Cell Prolymphocytic Leukemia and Richter's Syndrome. Among its related pathways are Hematopoietic cell lineage and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. GO annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.

Gene Symbol: CD38

Gen-ID: 952

UniProt: P28907