Nkx2-2 Antikörper

Produktnummer ABIN6296473

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Nkx2-2 in IF, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Huhn.

Kurzübersicht für Nkx2-2 Antikörper (ABIN6296473)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Nkx2-2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-Nkx2-2 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Chicken NKX2.2 Antibody [Sodium Azide Free]

Spezifität: Nuclear

Aufreinigung: Human NKX2.2 recombinant protein was used as the immunogen for this antibody.

Immunogen: Human NKX2.2 recombinant protein was used as the immunogen for this antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Andere Bezeichnung: Homeobox protein Nkx-2.2

Hintergrund:

Target Description: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.

Gene Symbol: NKX2-2///NKX2.2///NKX2B

Gen-ID: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis