CD3 epsilon Antikörper

Produktnummer ABIN6296157

Der Kaninchen Polyklonal anti-CD3 epsilon Antikörper (ABIN6296157) detektiert spezifisch CD3 epsilon in FACS, WB und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Schwein, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Huhn, Hund, Schaf, Hamster, Cat, Cryptomys amatus (Mole rat), Elephant, Frosch, Opossum und Primate.

Kurzübersicht für CD3 epsilon Antikörper (ABIN6296157)

Target: CD3 epsilon (CD3E)

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Huhn, Hund, Schaf, Hamster, Cat, Cryptomys amatus (Mole rat), Elephant, Frosch, Opossum, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD3 epsilon Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-CD3 epsilon Antikörper

Verwendungszweck: Rabbit anti-Human/Mouse/Rat/Primate/Guinea Pig/Hamster/Horse/Mole Rat/Pig/Rabbit/Sheep/Cat/Chicken/Cow/Dog/Frog/Opossum/Elephant CD3e Antibody [Sodium Azide Free]

Spezifität: Cell surface and cytoplasmic

Aufreinigung: Amino acids ERPPPVPNPDYEP (156-168) were used as the immunogen for this CD3e antibody.

Immunogen: Amino acids ERPPPVPNPDYEP (156-168) were used as the immunogen for this CD3e antibody.

Anwendungsinformationen

Applikationshinweise: FACS: use the CD3e antibody at 0.5-1 μg/million cells
WB: 0.5-1.0 μg/mL
IP: 1-2 μg/500 μg protein lysate,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CD3 epsilon

Target: CD3 epsilon (CD3E)

Andere Bezeichnung: T-cell surface glycoprotein CD3 epsilon chain

Hintergrund:

Target Description: This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.

Gene Symbol: CD3E///T3E

Gen-ID: 916

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway