Nkx2-2 Antikörper

Produktnummer ABIN6296003

Der Kaninchen Polyklonal Anti-Nkx2-2-Antikörper wurde für IF, IHC und FACS validiert. Er ist geeignet, Nkx2-2 in Proben von Human zu detektieren.

Kurzübersicht für Nkx2-2 Antikörper (ABIN6296003)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nkx2-2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-Nkx2-2 Antikörper

Verwendungszweck: Rabbit anti-Human NKX2.2 Antibody [Sodium Azide Free]

Spezifität: Nuclear

Aufreinigung: A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.

Immunogen: A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10e6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 minutes at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Andere Bezeichnung: Homeobox protein Nkx-2.2

Hintergrund:

Target Description: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.

Gene Symbol: NKX2-2///NKX2.2///NKX2B

Gen-ID: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis