VRK1 Antikörper (Center)

Produktnummer ABIN6295345

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VRK1 in . Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für VRK1 Antikörper (Center) (ABIN6295345)

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VRK1 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-VRK1 Antikörper

Bindungsspezifität: AA 366-396, Center

Verwendungszweck: Rabbit Anti-VRK1 (Center) Antibody

Immunogen: This VRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-396 amino acids from the Central region of human VRK1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu VRK1

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Andere Bezeichnung: VRK1

Hintergrund:

Target Description: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Gene Symbol: VRK1

Gen-ID: 7443

UniProt: Q99986