PGK1 Antikörper (Center)
Kurzübersicht für PGK1 Antikörper (Center) (ABIN6295138)
Target
Alle PGK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 117-145, Center
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Verwendungszweck
- Rabbit Anti-PGK1 (Center) Antibody
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Immunogen
- This PGK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the Central region of human PGK1.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
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Andere Bezeichnung
- PGK1
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Hintergrund
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Target Description: Also known as ATP:3-phosphoglycerate 1-phosphotransferase (EC 2.7.2.3), this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. New blood vessel formation or angiogenesis is critical for tumor expansion and metastasis. Lay et al. (2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. They concluded that phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and participates in the angiogenic process as a disulfide reductase.
Gene Symbol: PGK1
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Gen-ID
- 5230
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UniProt
- P00558
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Pathways
- Cellular Glucan Metabolic Process
Target
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