SUMO2 Antikörper (C-Term)

Produktnummer ABIN6294661

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SUMO2 in . Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für SUMO2 Antikörper (C-Term) (ABIN6294661)

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SUMO2 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-SUMO2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Mouse Anti-SUMO2 (C-term) Antibody

Immunogen: Purified His-tagged SUMO2 protein was used to produced this monoclonal antibody.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu SUMO2

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Andere Bezeichnung: SUMO2

Hintergrund:

Target Description: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

Gene Symbol: SUMO2

Gen-ID: 6613

UniProt: P61956

Pathways: Methionine Biosynthetic Process