VLDLR Antikörper (C-Term)

Produktnummer ABIN6294641

Der Maus Monoklonal Anti-VLDLR-Antikörper wurde für WB, IHC, FACS und IF validiert. Er ist geeignet, VLDLR in Proben von Human und Ratte zu detektieren.

Kurzübersicht für VLDLR Antikörper (C-Term) (ABIN6294641)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VLDLR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-VLDLR Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Mouse anti-Human/Rat VLDLR Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.

Immunogen: A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
Western blot: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Andere Bezeichnung: Very low-density lipoprotein receptor

Hintergrund:

Target Description: Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Gene Symbol: VLDLR

Gen-ID: 7436

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin