Involucrin Antikörper (AA 421-568)

Produktnummer ABIN6294531

Dieses Anti-Involucrin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Involucrin in IHC, IF und FACS. Geeignet für Human, Hund, Schwein, Gorilla und Owl Monkey.

Kurzübersicht für Involucrin Antikörper (AA 421-568) (ABIN6294531)

Target: Involucrin (IVL)

Reaktivität: Human, Hund, Schwein, Gorilla, Owl Monkey

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Involucrin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Involucrin Antikörper

Bindungsspezifität: AA 421-568

Verwendungszweck: Mouse anti-Human/Gorilla/Owl Monkey/Pig/Dog Involucrin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Purified involucrin from human keratinocytes was used as the immunogen for this Involucrin antibody. Its epitope maps between amino acids 421-568 of human involucrin.

Immunogen: Purified involucrin from human keratinocytes was used as the immunogen for this Involucrin antibody. Its epitope maps between amino acids 421-568 of human involucrin.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Involucrin

Target: Involucrin (IVL)

Andere Bezeichnung: Involucrin

Hintergrund:

Target Description: Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal, expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.

Gene Symbol: IVL

Gen-ID: 3713

UniProt: P07476